During times of high stress, travel, or medication use, your digestive system may be subjected to an accelerated decrease in beneficial bacteria. This decrease may be responsible for digestive discomfort including gas, bloating, and irregularity along with a weakened immune system.* UP4» ULTRA is doctor formulated to rapidly replenish the loss of this good bacteria. This proven formula was developed using our most diverse group of naturally occurring strains at our highest potency.